Episode 1

Twelve leading medical experts attempt to diagnose a man whose face has dramatically swollen and a woman who is sick whenever she tries to eat and is dramatically losing weight

Episode 2

Twelve medical experts race to diagnose a man with a life-threatening skin condition and a mother suffering a dramatic decline in health.

Episode 3

Michael Moseley challenges a team of doctors to diagnose a young woman struggling with dramatic weight gain and hair loss and another who has suddenly lost her sight in one eye.

Episode 4

A team of top doctors try to diagnose a man suffering multiple seizures every day and a young woman who has lived with a constant for nine years.