Starring Boris Karloff (also known as The Boris Karloff Mystery Playhouse) is an American radio and television anthology series broadcast for 13 weeks, September–December 1949, on the ABC network. Boris Karloff was the host and occasional star, with music by organist George Henninger. Produced and directed by Charles Warburton, the series adapted short stories of mystery and suspense.

22nd September 1949 - 15th December 1949