Episode 1

Though officially their uncle, Cardinal Rodrigo Borgia gathers his three children, but Juan's and Cesare's lack of control threaten his life's work.

Episode 2

When a plot to poison the pope is baffled and the pontiff's original testament restored, Cesare watches his brother rise further in Rodrigo's esteem.

Episode 3

A quarrel starts among the cardinals and old reckonings are being settled, while Cesare offers his son as a sacrifice to God, abandoning the newborn.

Episode 4

Rodrigo promises estates and offices for those voting in his favour, and when white smoke rises, he leaves the conclave as Pope Alexander VI.

Episode 5

The wedding of Lucrezia to Giovanni Sforza is to seal the union between the Borgia and Sforza families, but the marriage will not be consummated.

Episode 6

As peace remains brittle, Rodrigo publicly acknowledges his paternity of Juan, Cesare, Lucrezia and Goffredo to strengthen the family bonds.

Episode 7

Instead of keeping the peace, Rodrigo gives in to Giulia's urging and has his men take up arms, but under Juan's command the campaign fails.

Episode 8

With his enemies advancing and his troops deserting Juan's command, Rodrigo has to take a tough decision that puts Cesare's life at stake.

Episode 9

Rodrigo has his back on the wall as the French troops occupy the Eternal city, but thanks to his son Cesare, a fragile peace can be negotiated.

Episode 10

By the intervention of Spain, France is forced to withdraw, but Isabella of Spain demands a purge of the Jews from the Eternal City.

Episode 11

To prove himself worthy of the crown of Naples, Juan proposes to convert the Jews in a mass christening, but accidentally reveals a dark secret.

Episode 12

Cesare leads an investigative commission into Juan's death, but cannot find the guilty party and soon fears he himself killed his brother.