Based on the blockbuster films, this action-packed animated series starts a decade after the original Ghostbusters saved New York City from ghosts, goblins and ghouls. All the guys have left town, except Egon, now teaching a Paranormal Studies class at the local university. But Zuul, the all-powerful demon, has awakened from hibernation to wreak havoc on the unsuspecting masses. Desperate to recruit a new team, Egon and the plucky Janine turn to four of his teenage students: Kylie, a genius with an encyclopedic knowledge of the occult; Eduardo, a hip slacker with a crush on Kylie; Garrett, a wheelchair-bound athlete with a hot temper; and Roland, a “gentle giant” mechanical whiz. It's only a matter of time before Egon, Janine, old pal Slimer and the “kids” band together to rid the city of the evildoers.
Episode 1
Construction workers have inadvertantly released Achira, a ghost that can spread disease. The only ones who could stop this ghost are the Ghostbusters, but they have long since disbanded. In fact, only Egon is still in New York City. He is now teaching a college class, but his four students may prove very helpful against this nasty ghost.
Episode 2
Egon builds new and improved ghost busting equipment for the new team. While they search for Achira, Eduardo again sees Kylie, who has been possessed by Achira.
Episode 3
A Rabbi's son creates a Golem to defend against temple vandalism. But the Golem grows to strong to be controlled, forcing the EGB to come up against this violent force.
Episode 4
The EGB will have to face their inner demons when they come up against a ghost that can bring people's fears to life.
Episode 5
Characters from a horror novel are attacking innocent people.
Episode 6
A thief has gotten ahold of a pouch containing ancient runes, which a demon uses to enslave innocent people in his realm. The EGB have to catch this thief and rescue the demon's slaves.
Episode 7
A demon takes control of Roland and forces him to build a deadly mechanical host vehicle.
Episode 8
The EGB are on a job to bust a ghost, when they find the ghost is the house they're in and intent making two trapped children it's next meal.
Episode 9
Ghostly clowns are on the loose and feeding on laughter. Eduardo traps one of them, but then he starts to turn into one of them.
Episode 10
Everytime someone looks at the strange orb, a ghost appears to steal their eyes. Problem is, a museum is about to put the orb on display.
Episode 11
Janine attempts to make Egon jealous by going on a date with another man. Unfortunately, the man she dates is a bug demon in disguise and looking for a queen.
Episode 12
Ghosts are rampaging through the city and the EGB's equipment can't stop them. But a mysterious Piper claims he can.
Episode 13
A ghost capable of granting wishes comes to town in the form of a salesman, only his results are far from what people wanted. Eduardo unfortunately becomes his latest victim when he gets placed inside Kylie's cat.
Episode 14
A gremlin is on the loose, causing trouble throughout the city. While working to catch this gremlin, the EGB are arrested.
Episode 15
The equipment-less EGB have to protect a small town from the Jersey Devil.
Episode 16
A ghost capable of sucking all the water out of people is on the loose.
Episode 17
The EGB's hunt for a Banshee gets complicated when the Banshee's sister puts a spell on Roland.
Episode 18
Kylie gets transported to a future where a ghost named Tempus rules over humanity. While she meets a group of resistance fighters, the others have to prevent Tempus' take over in the present.
Episode 19
The weather in New York City is made a lot worse when a spirit called the Harasvelg arrives.
Episode 20
A Demon seed inhabits a Professor's plant, and takes over the building. The plant is destroyed, and the demon takes on another plant, in the park. Kylie thinks this demon is a helpful Amazon Plant, however she is wrong. It's really a civilization destroying demon inhabiting a seed. Can the EGB's stop Kylie before she has a chance to freeze it and send it back to the Amazon?
Episode 21
A recently released Leprechaun is trapping people in his pot of gold and Mayor McShane is his next target.
Episode 22
A ghost starts taking over people's bodies by pulling their souls into a mirror. When the others get trapped, it falls to Kylie to save the day.
Episode 23
Slimer gets trapped in the containment unit (and Peter Venkman isn't even here to see it), surrounded by some very vindictive ghosts that remember him, including a demon named Surt who wants to bring about Ragnarok. Eduardo goes in to save Slimer, while the rest of the EGB has to bust a demon hound in the Firehouse.
Episode 24
When Kylie was a child, a friend of her's mysteriously disappeared. Now, a ghost who looks like him has turned up. To stop and save him, Kylie calls upon a ghost the Real Ghostbusters captured years ago: the Grundel.
Episode 25
The EGB find their nightmares becoming more real when a ghost tries to leave the dream world and enter ours'.
Episode 26
The EGB have to join forces with a vengeful ghost to stop a ghost whale's rampage.
Episode 27
The EGB find their equipment useless against a radioactive energy eating ghost.
Episode 28
After a Chinatown merchant disappears, the EGB find the merchant has fallen prey to a bone stealing demon.
Episode 29
The EGB protect a man from a ghost that's looking to make a husband out of him.
Episode 30
The EGB have to contend with a ghost, whose victims go on feeding frenzies, looking to take over the world.
Episode 31
A reopened oil mine sets a ghost, that can possess vehicles, free.
Episode 32
A demon dog is enslaving all the dogs in the city. The EGB not only have to face that but also the demon dog's master.
Episode 33
There's been a string of power outages and the blame is falling to a group of people that live under the city. A young girl from the group gets help from the EGB, who find lightning demons are the real cause.
Episode 34
With Janine on vacation, the EGB hire a temp. But this temp is really an energy draining ghost planning to destroy the team.
Episode 35
Egon moves in with Eduardo while the Firehouse is sprayed for bugs and learns Eduardo hasn't told his brother what he does for a living. Meanwhile, the EGB go up against trolls with the power to replicate.
Episode 36
An old colleague of Egon's turns out to be behind a rash of ghost crimes.
Episode 37
Janine reunites Egon with Ray, Peter, and Winston for his 40th birthday but the Extreme Ghostbusters feel outclassed. Can both teams work together to take on a paranormal infestation?
Episode 38
The old team sticks around to help battle a mysterious entity that is heading to New York from the Bermuda Triangle and devouring everything in its path.
Episode 39
A sphinx starts tampering with people’s minds when they can’t find a way to answer the riddle.
Episode 40
Three teenage witches try to bring Kylie into their circle.
