Ishida & Asakura focuses on the title characters—the stoic Ishida and the lecherous Asakura—and the bizarre students and teachers that populate their high school. Asakura is obsessed with curvaceous women and dreams of becoming a teacher in order to be surrounded by attractive girls all day. Ishida dreams of running a flower shop together with Asakura after they finish high school, and appears to have strong homosexual feelings for his best friend, although this is always played for laughs.
Episode 1
Asakura is high school senior and he's squarely focused on one thing... boobs. But the rest of his classmates all seem to be focused on him!
Episode 2
Asakura's future gets further in doubt when his test scores come in. Ishida decides it's time for some extreme training!
Episode 3
After a long lecture in class, the boys all feel a need to relieve themselves, but they're surprised by an unexpected guest.
Episode 4
Asakura is worried about startup funds, and then everyone gets fraudulent phone calls asking for money.
Episode 5
Asakura and friends have a new teacher in class, and he's fired up about education! But can he deal with students like these?
Episode 6
Asakura saves Kinoshita-sensei's daughter from a traffic accident, and it would seem to be fate, but something is missing from the equation.
Episode 7
Yamada constructs a robot assassin to get rid of his rival, but it doesn't go as planned.
Episode 8
Ishida needs to earn 10 million yen to open up his flower shop, so he takes a job at a local cafe.
Episode 9
Yamada has a thing for Alice, the new maid at the maid cafe. When he discovers Ishida frequenting the shop, the battle lines are drawn!
Episode 10
Ishida kills Yamada again on the way to school, and his little sister vows revenge.
Episode 11
Ishida, to his shock, discovers that one has to be able to smile to run a flower shop, so Asakura and friends try to help him learn.
Episode 12
Ishida try to save Asakura which fell from the bridge. With burst of superhuman strength he throws him into atmosphere, accidentally hitting an UFO. Naked Asakura (whose clothes burned during flight through atmosphere) and Ishida are then found by teachers and colleagues, who confirm, that somebody shot down an UFO. Later on all girls with Kinoshita-sensei are on board of another UFO, but planned alien invasion on Earth was stopped by Kinoshita-sensei.
