An insecure but courageous and intelligent teen named Peter Parker, a new student of Midtown High, is bitten by a radioactive spider and given powers. He becomes a hero named Spider-Man after the death of his uncle and he must adapt to this new way of life.
Episode 1
Peter is accepted into Horizon High: a school for geniuses, where his best friend Harry Osborn was just suspended. Peter makes his debut as Spider-Man and must battle the Vulture.
Episode 2
Spider-Man must work to stop the Scorpion from wreaking havoc at the museum.
Episode 3
Norman Osborn creates the Osborn Academy for Geniuses as a way of saving his son, Harry, the embarrassment of being suspended from Horizon High.
Episode 4
Spider-Man must stop Black Cat from committing a spree of thefts while still keeping his school obligations.
Episode 5
Horizon High throws a dance in honor of Harry being exonerated, but Norman asks Harry to stay at the Oz Academy.
Episode 6
Spider-Man meets the powerful, yet uncontrollable Sandman and helps him reunite with his estranged daughter with the help of the Venom symbiote.
Episode 7
When Spider-Man uses his new black costume, he discovers that there is great danger in his new power; and he must find a way to defeat a costume that wants to destroy him.
Episode 8
After the terror of the symbiote, Spidey is off to the Stark Expo in his old costume. When Ghost hijacks the event, Spidey's only chance to save lives is to unleash the symbiote.
Episode 9
When Miles Morales is bitten by an experimental spider and gains spider powers, Spider-Man must teach him the responsibilities of being a superhero.
Episode 10
Kraven the Hunter does a live broadcast of his hunt for Spider-Man.
Episode 11
On Halloween night, Spider-Man must team up with the incredible Hulk to stop Man-Wolf, a super-strong gamma-powered werewolf, from infecting the rest of Manhattan.
Episode 12
Spidey must stop a low-level villain who has acquired some impressive freezing technology.
Episode 13
The symbiote has escaped the Avengers Compound and attached itself to a new host. Now Spidey must find out how to beat it and who the new person is underneath.
Episode 14
Spider-Man is targeted by a new costumed figure named Screwball for a series of online prank videos which block him from fighting crime.
Episode 15
When Otto Octavius is caught in an explosion that fuses his robot arms to his body, Spider-Man sees the opportunity to recruit "The Octopus" into becoming a hero.
Episode 16
Spidey invites The Octopus to patrol the streets alongside Miles and himself until it becomes clear that Otto isn't exactly a team player.
Episode 17
Peter spends a day at Osborn Academy in the hopes of finding a clue that will convince Harry that his father is out to destroy Spider-Man.
Episode 18
Spider-Man must team up with Gwen Stacy and a reluctant Harry Osborn to investigate the truth behind the missing Raymond Warren aka the Jackal.
Episode 19
Spider-Man tracks a new villain with spider powers who steals his experimental stealth suit and threatens the entire city.
Episode 20
Everyone in Manhattan manifests spider powers; Spider-Man and Spider-Gwen must help Black Widow track down Crossbones before he delivers the vibranium to Arnim Zola and Hydra.
Episode 21
Peter must find a way to cure Gwen Stacy and Norman Osborn after they turn into spider monsters; things get harder when Kraven the Hunter turns New York into his hunting grounds.
Episode 22
Peter and Harry must battle through an island of spider monsters to get to Norman Osborn, who appears to control them all; the boys discover the real mastermind.
Episode 23
To cure the spider-monster population of Manhattan, Spider-Man must lead Kid Arachnid, Anya and Harry on a desperate, last-ditch effort to stop the Jackal.
Episode 24
Spider-Man takes on Doc Ock and his Sinister Five before they brainwash Spidey and destroy New York City.
Episode 25
Spider-Man must find a way to stop Hobgoblin, who seems completely bent on doing whatever it takes to destroy Spider-Man.
